Nausea & Vomiting
1 Rumination is best related to ?
A. Nausea
B. Vomiting
C. Regurgitation
D. All of the above
2 Under normal conditions, frequency of slow wave cycles in the stomach is ?
A. 3 cycles / minute
B. 6 cycles / minute
C. 9 cycles / minute
D. 12 cycles / minute
3 Under normal conditions, frequency of slow wave cycles in the duodenum is ?
A. 4 cycles / minute
B. 8 cycles / minute
C. 11 cycles / minute
D. 15 cycles / minute
4 Which of the following is termed the chemoreceptor trigger zone ?
A. Area postrema
B. Nucleus tractus solitarius
C. Dorsal vagal nuclei
D. Phrenic nuclei
5 Which of the following act on the area postrema ?
A. Uremia
B. Hypoxia
C. Ketoacidosis
D. All of the above
6 Neurotransmitter that mediate induction of vomiting in labyrinthine disorders is ?
A. Muscarinic M1 receptors
B. Histaminergic H2 receptors
C. Serotonin 5-HT3 receptors
D. Dopamine D2 receptors
7 Gastroparesis occurs after which of the following ?
A. Pancreatic adenocarcinoma
B. Mesenteric vascular insufficiency
C. Scleroderma
D. All of the above
8 Gastroparesis does not occur with which of the following ?
A. Diabetes
B. Amyloidosis
C. Scleroderma
D. Cyclic vomiting syndrome
9 Which of the following drugs is a highly emetogenic agent ?
A. Digoxin
B. Oral contraceptives
C. Cisplatin
D. Erythromycin
10 What proportion of pregnant women experience nausea in the first trimester ?
A. 25 %
B. 50 %
C. 70 %
D. 90 %
11 Relief of abdominal pain by emesis is characteristic of ?
A. Pancreatitis
B. Zenker’s diverticulum
C. Gastric obstruction
D. Intestinal obstruction
12 Which of the following antiemetic agent is a Serotonin5-HT3 antagonist ?
A. Meclizine
B. Granisetron
C. Mirtazapine
D. Dimenhydrinate
13 Which of the following is a combined 5-HT4 agonist and D2 antagonist ?
A. Metoclopramide
B. Domperidone
C. Erythromycin
D. Octreotide
14 Which of the following is a Neurokinin NK1 antagonist ?
A. Aprepitant
B. Kevetiracetam
C. Cyproheptadine
D. Sumatriptan
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