Inflammatory bowel disease
1 Out of the following, which ethnic group has the highest prevalence of IBD ?
A. Jewish
B. African American
C. Hispanic
D. Asian
2 Nonmalignant mortality in IBD cases is maximum during ?
A. First year of disease
B. After five years of disease
C. After ten years of disease
D. After fifteen years of disease
3 If a patient has IBD, the lifetime risk that a first degree relative will be similarly affected is ?
A. 10 %
B. 20 %
C. 30 %
D. 40 %
4 Which of the following statements about Ulcerative colitis (UC) and Crohn’s disease (CD) is false ?
A. Peak age of onset of UC & CD is 15 - 30 years
B. Second peak occurs between 60 - 80 years
C. Appendectomy aggravates UC
D. IBD runs in families
5 Which genetic disorder is a predisposing factor for IBD ?
A. Turner’s syndrome
B. Down syndrome
C. Patau syndrome
D. Edward syndrome
6 IBD is associated with all of the following except ?
A. Turner’s syndrome
B. Down syndrome
C. Selective IgA deficiency
D. Hereditary angioedema
7 All of the following are predisposing factors for UC except ?
A. Jewish ethnicity
B. High socio-economic status
C. Smoking
D. Hermansky-Pudlak syndrome
8 If two parents have IBD, what chance does each child has of being affected ?
A. 36 %
B. 45 %
C. 66 %
D. 72 %
9 Which of the following is not associated with increased risk of UC ?
A. Urban domicile
B. High socio-economic status
C. Former smoker
D. Appendectomy
10 Disease that are shares genetic risk factors with IBD is ?
A. Rheumatoid arthritis
B. Psoriasis
C. Systemic lupus erythematosus
D. All of the above
11 Which of the following is not a probiotic ?
A. Lactobacillus sp.
B. Taenia suis
C. Campylobacter sp.
D. Saccharomyces boulardii
12 What proportion of UC patients have involvement of whole colon ?
A. 10 %
B. 20 %
C. 30 %
D. 40 %
13 Backwash ileitis occurs when which part of colon is involved in UC ?
A. Ascending colon
B. Transverse colon
C. Descending colon
D. Whole colon
14 Psychosocial factors can contribute to worsening of symptoms in which of the following illnesses ?
A. IBD
B. Chronic back pain
C. Amyotrophic lateral sclerosis
D. All of the above
15 Which of the following statements about pathology of Ulcerative colitis (UC) is false ?
A. Mucosal disease involving rectum and colon
B. Proximal spread occurs in continuity
C. Sandpaper like appearance of mucosa reflects severe inflammation
D. Inflammatory polyps (pseudopolyps) are due to epithelial regeneration
16 Which of the following statements about pathology of Ulcerative colitis (UC) is false ?
A. Limited to mucosa & superficial submucosa
B. Crypt architecture of colon is preserved
C. Basal lymphoplasmacytosis suggests chronicity
D. Cryptitis and crypt atrophy
17 Which of the following statements about pathology of Crohn’s disease (CD) is false ?
A. Can affect any part of gastrointestinal tract
B. Terminal ileum involved in 90% of patients
C. Rectum is always involved in CD
D. Segmental with skip areas
18 Which of the following statements about pathology of Crohn’s disease (CD) is false ?
A. Perirectal fistulas, abscesses & anal stenosis common
B. Never involves liver & pancreas
C. Transmural process
D. “Cobblestone” appearance on endoscopy
19 “Cobblestone mucosa” in CD is mainly seen in ?
A. Sigmoid colon
B. Transverse colon
C. Ileum
D. Rectum
20 Which of the following statements about pathology of Crohn’s disease (CD) is false ?
A. Earliest lesions are aphthoid ulcerations & focal crypt abscesses
B. Caseating granulomas in all bowel wall layers common
C. Granulomas can be seen in liver & pancreas
D. Granulomas can be seen in lymph nodes, mesentery, peritoneum
21 In CD, “Creeping fat” is the term given to ?
A. Excessive enlargement of omentum
B. Necrosis of omentum
C. Projections of thickened mesentery encasing bowel
D. Fatty adhesions
22 Which of the following is not a major symptom of UC ?
A. Rectal bleeding
B. Constipation
C. Crampy abdominal pain
D. Tenesmus
23 Which of the following statements about clinical features of Ulcerative colitis (UC) is false ?
A. Tenesmus is a major symptom
B. Severity of symptoms do not correlate with extent of disease
C. Constipation seen in patients with distal disease
D. Diarrhea is often nocturnal and/or postprandial
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