Neutropenia

1. Senescent neutrophils are cleared from the circulation by macrophages in ?

A. Kidneys
B. Lung
C. GI tract
D. Thymus


2. Characteristic green color to pus is due to ?
A. Collagenase
B. Elastase
C. Myeloperoxidase
D. All of the above

3. Susceptibility to infectious diseases increases sharply when neutrophil counts fall below ?
A. 1000 cells/μL
B. 2000 cells/μL
C. 3000 cells/μL
D. 4000 cells/μL

4. Inflammatory process is absent, when absolute neutrophil count (ANC) falls below ?
A. < 100 cells / μL
B. < 200 cells / μL
C. < 500 cells / μL
D. < 1000 cells / μL


5. Neutropenia can be due to ?
A. Depressed production
B. Increased peripheral destruction
C. Excessive peripheral pooling
D. All of the above


6. Which of the following drugs cause neutropenia due to decreased production ?
A. Carbamazepine
B. Clozapine
C. Antithyroid drugs
D. All of the above


7. Which of the following drugs act as haptens to cause neutropenia due to peripheral destruction ?
A. Alpha methyldopa
B. Phenylbutazone
C. Mercurial diuretics
D. All of the above


8. Which of the following is a cause of neutropenia due to peripheral pooling (Transient neutropenia) ?
A. Overwhelming bacterial infection (acute endotoxemia)
B. Hemodialysis
C. Cardiopulmonary bypass
D. All of the above


9. Congenital forms of neutropenia include ?
A. Kostmann’s syndrome
B. Shwachman-Diamond syndrome
C. WHIM syndrome
D. All of the above


10. Felty’s syndrome include all except ?
A. Rheumatoid arthritis
B. Hepatomegaly
C. Splenomegaly
D. Neutropenia